no harsh chemicals if you intend keeping them
gentle soap and water and a scrub.
most crystals "feel better in the hand" after being placed in salt water solution outside in the sun for a day or two , or left out under a full moon
exception being rose quartz and a few others which lose their colour if put in salt water
If people buy crystals after they have been cut / polished / mounted etc , they often want to pick them up and feel them in their hand before buying
harsh chemicals might take away the warm feeling or vibrancy that many crystals possess naturally