Dan. If you have only just got it, may I recommend:
Both Channels on.
Threashold just audible (use a small piece of aluminium on the ground when you start it up.) Consider an audio booster - the 2200s have a bad (deserved) reputation for soft audio.
Use tracking but once you get used to rebalancing as you go, switch to fixed - you get more depth.
Deep setting.
Discriminator is a tricky bit of advice. I have it off unless I am in really trashy ground. There are some very true stories of big gold washing out the discriminator on these 22s.
Try and get good headphones with an audio boost (volume switches) - those poxy elcheapo Koss sets are crXp. (they used to come as standard with the 4500/5000)
Do some research on how to use a DD - they are different from a mono in coverage, areas where the coil is less sensitive (the head usually). For example, you can walk straight at a tree with a mono, you need to sweep around a tree with a DD with the edge to the tree. Thats why if you are in scrubby ground a smaller DD is need to sweep side to side under close scrub, not nose in, you may miss some small gold.
When they first came out, man, did we think we were in heaven with the 22s. I
The discriminator over trashy ground will defeat the latest and greatest monos hands down any day of the week. I say they are probably one of the best training detectors there is. The next best trainer in my opinion is the 3500.
Problems they have? Audio as described. Ground noise can be an issue and you can only learn how to deal with this by practice but trust me, a lot of us still dig ground noises!!
Good luck - get the old beast humming along and you will be very pleased.